By: Sarah L. Johnson, MD, MPH, Ph. D., is the Director of the Division of Sexual Health at the American Academy of Sexual Medicine (AAMS), an affiliate of the American Sexual Medicine Association.
For this article, I will be focusing primarily on the effects of sildenafil citrate on the sexual life of men. I will discuss how this medication works, how it impacts sexual functioning, and the possible side effects associated with the drug.
In 1998, researchers at the University of California, San Francisco, determined that sildenafil citrate can significantly improve erectile function in men with erectile dysfunction (ED). The researchers found that, in some men, the drug caused a marked improvement in their sexual functioning compared to placebo. In particular, they found that the drug was effective in improving erectile function in both men and women. As men's sexual health is closely linked to erectile function, a person's ability to maintain and sustain an erection can be impaired by sildenafil citrate.
It has been suggested that sildenafil citrate may not be as effective as some other ED medications, particularly those containing the phosphodiesterase type 5 (PDE5) inhibitors, and that other medications, such as sildenafil citrate, may interact with sildenafil citrate, increasing the risk of side effects. This is in contrast to many other ED medications, including Viagra, that work well with sildenafil citrate.
I want to highlight how this drug works in the sexual lives of men. The drug is a phosphodiesterase type 5 (PDE5) inhibitor that helps with the flow of blood and nerve impulses to the penis. It works by relaxing the blood vessels in the penis, allowing the blood to flow into the penis and produce an erection. When this occurs, it causes the muscles in the penis to relax and increase blood flow, allowing for the achievement and maintenance of an erection. By blocking the PDE5 enzyme in the penis, sildenafil citrate helps to increase the flow of blood in the penis. This increased blood flow helps men achieve and maintain erections for satisfactory sexual performance.
It is important to note that sildenafil citrate does not cure ED, and it is not a cure for erectile dysfunction. Sexual dysfunction is a normal part of aging, and sildenafil citrate is often used for other conditions, such as erectile dysfunction or pulmonary arterial hypertension.
The erectile dysfunction drugs that have been studied for sexual dysfunction are sildenafil citrate and nitrates. Viagra and other erectile dysfunction drugs are often taken over the counter (OTC) or as a recreational drug. Sildenafil citrate is a phosphodiesterase type 5 (PDE5) inhibitor that is effective in the treatment of erectile dysfunction and pulmonary arterial hypertension.
The most common side effects of sildenafil citrate include headache, flushing, back pain, muscle aches, nausea, dizziness, and fatigue. It is important to note that these side effects are usually mild and temporary. However, they can be severe and require prompt medical attention. If sildenafil citrate is used with nitrates, then a serious adverse reaction may occur. It is important to note that nitrates, which contain aspartame, the active ingredient in the prescription form of sildenafil citrate, can cause a serious drop in blood pressure when combined with sildenafil citrate. This can be dangerous, especially in the presence of heart disease, kidney disease, and certain other conditions.
In addition to the above side effects, there are also some more serious adverse effects of sildenafil citrate that are not listed above.
The cheapest erectile dysfunction (ED) pills are generic Viagra, called.
The term "generic" refers to the active ingredient of a medicine or drug rather than to the advertised brand name under which the medicine is sold. It is a term referring to any drug marketed under its chemical name without advertising.
Pfizer made the originaltablet that is often referred to as the “blue pill”.The patent expired in 2013 which then allowed other pharmaceutical manufactures to make a generic version under the name of the active ingredient called Sildenafil. They are exactly the same medically and perform in the same way with the same side-effects.
As with most branded products, Viagra is sold at a higher price,therefore the generic tablets sold asare much cheaper.
Medically there is no difference between a generic medicine and the branded medicine, as they both have the same active ingredients to make them perform in the same way. They only differ in the “bulking” agents used to fill the tablet as the amount of active ingredient required, in this case Sildenafil, is very small. This makes the tablets bigger and easier to handle.
The main difference between generic andbranded named prescription medicines is cost with generics being much cheaper
Every pharmacy can choose what price they sell at, as there are no fixed prices. It will depend on what price the pharmacy can buy the drug from the wholesaler and the cost of their own overheads. They can they decide what mark-up they require and some pharmacies choose to sell some products at higher prices.
At Webmed pharmacy we aim to keep our prices as low as possible, without compromising the quality of service, as we arethe only online pharmacy to offercourier guaranteed next working day as standard
We offer a very fast, confidential and discreet service that isby the General Pharmaceutical Council (GPhC) and the Care Quality Commission (CQC).
A large proportion of our sales are made up of returning customers as they have been delighted with our service.
When you choose to buy any prescription medication online, you must first of check that the pharmacy is with the General Pharmaceutical Council (GPhC).
All pharmacies using a UK General Medical Council, to prescribe their medicines will also be registered with the UK government Agency the Care Quality Commission (CQC).
Those online pharmacies who are not registered with the CQC either use pharmacist prescribers or foreign doctors.
You will then know and have the confidence that all the brands being offered are genuine and will work in the same way. All the pharmaceutical companies are inspected by the Medicines and Healthcare products Regulatory Agency (MHRA) to ensure they manufacturer the drugs to the same quality standard. This means that the key ingredient that is referred to as the “active” ingredient is exactly the same in all brands.
The other inactive ingredients that make up the bulk of the tablet are called “excipients” and can vary.
For those people who are allergic to or have an intolerance to lactose, then the is ideal for you as it is lactose free. You can check the additional excipients on the patient information leaflet supplied with your tablets.
Although medically all the generic tablets are identical, they may look different as they can vary in colour, shape and size due to the varying excipients.
The patent for, owned by Pfizer, expired in July 2013, which then allowed other pharmaceutical companies to produce generic. There are a number of companies now manufacturing which include Accord, Ajanta, Dr Reddy’s, Mylan, Teva, Torrent and Zentiva. Even Pfizer make a that they sell cheaper than Viagra although generally more expensive than the equivalent generic brands.
Author 19th September 2019
AEciplinary White paper(ots)1. MHRA inspectedGeneric with (osis) in July 20042. MHRA approval (tier 3)3. AstraZeneca Approved generic3. generic4. Pfizer Approves Viagra5. Zentiva Approved generic6.
Note: Other medications can affect how Sildenafil is processed in your body, potentially impacting its effectiveness. These include azole antifungals (such as itraconazole or ketoconazole), macrolide antibiotics (such as clarithromycin or erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, and ritonavir.
Combining Sildenafil with other medications for erectile dysfunction (ED) or pulmonary hypertension, such as tadalafil or vardenafil, is harmful.
Note:Sildenafil can interact with other medications and products you uses, so missing or not using your test medications, especially if you're taking other medications that you nitrate, or even if you have certain medical conditions, such as severe heart failure or high blood pressure, can result in interactions. This list does not include all potential interactions.Do not take Sildenafil if you:
These may or may not affect how you feel on one level or affect the other. If you feel better directly you can take Sildenafil. If you feel worse of for on another level, contact your doctor. You may feel better by or around the other medication. You should contact your doctor byounces level if you're taking Sildenafil for an eye disease.
This level is based on your medical condition and may be the same as the LFT your doctor will prescribe.
Sildenafil works by “bioovery,” which means that it’s a process of breakdown. It typically takes several days before you experience results. Keep using this medicine as directed by your doctor. If you miss a dose, simply skip the missed dose. You may keep using the medicine byounces dose as you remember it.
You should take your medicine at the most commonly used dose for your dose to suit your needs.
Avoid taking more than the prescribed dose without consulting your doctor.
Sildenafil can cause various side effects. However, these are a few of the most common.
Sildenafil often leads to a sense of pressure. This can be a sign of an erection. Or it can be a sign of an intolerance to some chemicals in Sildenafil. In some cases, these side effects may be more common than they actually are.
Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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Product descriptionErectile dysfunction is the inability to get or keep an erection sufficient for sexual activity. Erectile dysfunction is the inability to obtain an erection sufficient for sexual activity. It is important to understand that Sildenafil is not a cure for ED and will help you achieve and maintain an erection when sexually aroused. Sildenafil will only help you achieve and maintain an erection when you are sexually aroused.
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